As you gather a body of literature, it is important to learn how to critically appraise a clinical research paper. This helps
From the Centre for Evidence Based Medicine
As part of critically appraising an article, you also need to assess the risk of bias. Risk of bias is defined as the risk of systematic error in results or inferences. This is important as the development of sophisticated quasi-experimental study designs, and systematic reviews are increasingly incorporating non-randomized studies into evidence syntheses.
Below are some methodological tools you can use for critically appraising an article and assessing the risk of bias, based on study design.